The role of pleiotrophin and β-catenin in fetal lung development

被引：0

作者：

Tingting Weng

Lin Liu

机构：

[1] Oklahoma State University,Lundberg

来源：

Respiratory Research | / 11卷

关键词：

Idiopathic Pulmonary Fibrosis; Anaplastic Lymphoma Kinase; Alveolar Epithelial Cell; Lung Development; Epithelial Cell Differentiation;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Mammalian lung development is a complex biological process, which is temporally and spatially regulated by growth factors, hormones, and extracellular matrix proteins. Abnormal changes of these molecules often lead to impaired lung development, and thus pulmonary diseases. Epithelial-mesenchymal interactions are crucial for fetal lung development. This paper reviews two interconnected pathways, pleiotrophin and Wnt/β-catenin, which are involved in fibroblast and epithelial cell communication during fetal lung development.

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