Anti-angiogenic therapies in brain metastases

被引:24
作者
Berghoff A.S. [1 ]
Preusser M. [1 ]
机构
[1] Department of Medicine I and Comprehensive Cancer Center Central Nervous System Tumours Unit (CCC-CNS), Medical University of Vienna, Währinger Gürtel 18–20, Vienna
关键词
Asymptomatic; Bevacizumab; CNS metastases; Symptomatic; Systemic treatment;
D O I
10.1007/s12254-018-0384-2
中图分类号
学科分类号
摘要
Brain metastases are a major challenge in modern oncology, as treatment options upon the diagnosis of symptomatic brain metastases are limited. Neo-angiogenesis was identified as a hallmark of brain metastasis development and inhibition using anti-angiogenic therapy might therefore be an experimental promising preventive as well as therapeutic approach. The current review will summarize the current available data on the efficacy of neo-angiogenic therapies in patients with brain metastases. © 2018, The Author(s).
引用
收藏
页码:14 / 17
页数:3
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