Hematological responses to hydroxyurea therapy in multitransfused thalassemic children

被引：13

作者：

Choudhry V.P. ^{[1
,2
]}

Lal A. ^{[1
]}

Pati H.P. ^{[1
]}

Arya L.S. ^{[1
]}

机构：

[1] Depts. of Hematology and Pediatrics, All India Inst. of Medical Sciences, Ansari Nagar

[2] Department of Hematology, All India Inst. of Medical Sciences, Ansari Nagar

来源：

The Indian Journal of Pediatrics | 1997年 / 64卷 / 3期

关键词：

Hydroxyurea therapy; Multi transfused thalassemic;

D O I：

10.1007/BF02845212

中图分类号：

学科分类号：

摘要：

Fifteen multi-transfused thalassemic children between 3-6 years of age (seven boys and eight girls) were administered hydroxyurea for 5 days and three such cycles were repeated at 15 days interval. Rise in hemoglobin levels was observed in 13, 8 and 7 cases, while rise in mean hemoglobin F was seen in 8, 11 and 10 cases following 1st, 2nd and 3rd course of hydroxyurea therapy respectively. Rise in hemoglobin level was associated with transient rise in fetal hemoglobin level. Though the changes in mean hemoglobin levels and hemoglobin F levels were statistically insignificant, a definite trend of rise in hemoglobin and hemoglobin F was observed.

引用

页码：395 / 398

页数：3

共 14 条

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