microRNA-26a suppresses recruitment of macrophages by down-regulating macrophage colony-stimulating factor expression through the PI3K/Akt pathway in hepatocellular carcinoma

被引:0
作者
Zong-Tao Chai
Xiao-Dong Zhu
Jian-Yang Ao
Wen-Quan Wang
Dong-Mei Gao
Jian Kong
Ning Zhang
Yuan-Yuan Zhang
Bo-Gen Ye
De-Ning Ma
Hao Cai
Hui-Chuan Sun
机构
[1] Liver Cancer Institute,Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education
[2] Zhongshan Hospital,Department of Pancreatic and Hepatobiliary Surgery
[3] Fudan University,Department of Oncology, Shanghai Medical College
[4] Fudan University,Pancreatic Cancer Institute
[5] Fudan University Shanghai Cancer Center,Department of Hepatobiliary Surgery
[6] Fudan University,undefined
[7] Fudan University,undefined
[8] Beijing Chaoyang Hospital,undefined
[9] Capital Medical University,undefined
来源
Journal of Hematology & Oncology | / 8卷
关键词
microRNA-26a; Hepatocellular carcinoma; M-CSF; Macrophages;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 346 条
[1]  
Forner A(2012)Hepatocellular carcinoma Lancet. 379 1245-55
[2]  
Llovet JM(2005)Hepatocellular carcinoma surgery—review of the past and prospects for the 21st century J Surg Oncol. 91 95-6
[3]  
Bruix J(2011)The tumor microenvironment in hepatocellular carcinoma: current status and therapeutic targets Semin Cancer Biol. 21 35-43
[4]  
Tang ZY(2014)Clearance of senescent hepatocytes in a neoplastic-prone microenvironment delays the emergence of hepatocellular carcinoma Aging (Albany NY). 6 26-34
[5]  
Yang JD(2006)Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment Cancer Cell. 10 99-111
[6]  
Nakamura I(2008)High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma J Clin Oncol. 26 2707-16
[7]  
Roberts LR(2011)Cancer-promoting tumor-associated macrophages: new vistas and open questions Eur J Immunol. 41 2522-5
[8]  
Marongiu F(2009)Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation J Leukoc Biol. 86 1065-73
[9]  
Serra MP(2009)Cellular and molecular pathways linking inflammation and cancer Immunobiology. 214 761-77
[10]  
Sini M(2010)Macrophages, innate immunity and cancer: balance, tolerance, and diversity Curr Opin Immunol. 22 231-7