Changes in the activity and protein levels of CSF acetylcholinesterases in relation to cognitive function of patients with mild Alzheimer’s disease following chronic donepezil treatment

被引：0
作者：
T. Darreh-Shori
L. Meurling
T. Pettersson
K. Hugosson
E. Hellström-Lindahl
N. Andreasen
L. Minthon
A. Nordberg
机构：
[1] Karolinska University Hospital Huddinge,Division of Molecular Neuropharmacology, Department of Neurobiology, Care Sciences and Society, Karolinska Institute
[2] Karolinska University Hospital Huddinge,Department of Geriatric Medicine
[3] Karolinska University Hospital Huddinge,Labmedicin, Division for Clinical Pharmacology
[4] University Hospital MAS,Neuropsychiatric Clinic
来源：
Journal of Neural Transmission | 2006年 / 113卷
关键词：
Keywords: Alzheimer’s disease, acetylcholinesterase, acetylcholinesterase splice variants, cholinesterase inhibitors, cerebrospinal fluid (CSF), red blood cells (RBC), chronic treatment, donepezil;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Objectives. To evaluate long-term changes in acetylcholinesterase (AChE) activity in CSF and blood following donepezil treatment in relation to the concentration of donepezil and cognition in AD patients.
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页码：1791 / 1801
页数：10
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