Post-stroke affective or apathetic depression and lesion location: left frontal lobe and bilateral basal ganglia

被引：0
作者：
Seiji Hama
Hidehisa Yamashita
Masaya Shigenobu
Atsuko Watanabe
Kaoru Kurisu
Shigeto Yamawaki
Tamotsu Kitaoka
机构：
[1] Nishi-Hiroshima Rehabilitation Hospital,Department of Rehabilitation
[2] Graduate School of Biomedical Science,Department of Psychiatry and Neuroscience
[3] Hiroshima University,Department of Neurosurgery
[4] Graduate School of Biomedical Science,undefined
[5] Hiroshima University,undefined
[6] Nishi-Hiroshima Rehabilitation Hospital,undefined
来源：
European Archives of Psychiatry and Clinical Neuroscience | 2007年 / 257卷
关键词：
basal ganglia; frontal lobe; stroke; apathy; Zung Self-rating Depression Scale;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This study was designed to examine the correlation between damage to the basal ganglia or frontal lobe and depression status (both affective and apathetic dimensions) in 243 stroke patients. We assessed the affective dimension in post-stroke depression (PSD) using the Zung Self-rating Depression Scale (SDS) and the apathetic dimension in PSD using the apathy scale (AS). We classified basal ganglia or frontal lobe damage into four groups: no damage, damage to the left side only, damage to the right side only, and damage to both sides. Affective and/or apathetic PSD was found in 126 patients (51.9%). The severity of affective depression (SDS score) was associated with left frontal lobe (but not basal ganglia) damage, and that of apathetic depression (AS score) was related to damage to the bilateral basal ganglia (but not to the frontal lobe). The anatomical correlates of PSD differ depending on the PSD dimension (affective or apathetic) and may explain interstudy differences regarding the association between lesion location and type of PSD.
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页码：149 / 152
页数：3
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