Initial Stages of 2,4,6-Trinitrotoluene Transformation by Microorganisms

被引：0
作者：
S. A. Zaripov
A. V. Naumov
E. S. Suvorova
A. V. Garusov
R. P. Naumova
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来源：
Microbiology | 2004年 / 73卷
关键词：
Toxic Effect; Natural Environment; Aromatic Ring; Collection Strain; Reductive Attack;
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摘要：
Screening of a wide range of microorganisms (32 strains) isolated from various anthropogenic and natural environments and of a number of collection strains showed that the early stages of 2,4,6-trinitrotoluene (TNT) transformation by the majority of the strains studied resulted in the formation of hydroxylaminodinitrotoluenes (HADNTs). The levels of HADNTs were in a number of cases comparable to the initial TNT level. The alternative reductive attack on TNT through the reduction of the aromatic ring was not characteristic of most of the prokaryotes studied. The susceptibility to the toxic effect of TNT was different for gram-positive and gram-negative bacteria.
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页码：398 / 403
页数：5
相关论文
共 51 条
[1]  
George S.E.(2001)Initial Reductive Reactions in Aerobic Microbial Metabolism of 2,4,6-Trinitrotoluene Use of a Salmonella Microsuspension Bioassay to Detect the Mutagenicity of Munitions Compounds at Low Concentrations, Mutat. Res. 490 45-56
[2]  
Huggins-Clark G.(2002)Aerobic Degradation of 2,4,6-Trinitrotoluene by Enterobacter cloacae PB2 and by Pentaerythritol Tetranitrate Reductase Alternative Pathways of the Initial Transformation of 2,4,6-Trinitrotoluene by Yeasts, Mikrobiologiya 71 648-653
[3]  
Brooks L.R.(1998)Initial-Phase Optimization for Bioremediation of Munition Compound-Contaminated Soils Appl. Environ. Microbiol. 64 246-252
[4]  
Zaripov S.A.(1998)Screening for Fungi Intensively Mineralizing 2,4,6-Trinitrotoluene Appl. Environ. Microbiol. 64 2864-2868
[5]  
Naumov A.V.(1993)Inhibition of the Lignin Peroxidase of Phanerochaete chrysosporium by Hydroxylamino-Dinitrotoluene, an Early Intermediate in the Degradation of 2,4,6-Trinitrotoluene Appl. Environ. Microbiol. 59 2171-2177
[6]  
Nikitina E.V.(1997)Aerobic Gram-Positive and Gram-Negative Bacteria Exhibit Differential Sensitivity to and Transformation of 2,4,6-Trinitrotoluene (TNT) Appl. Microbiol. Biotechnol. 47 452-457
[7]  
Naumova R.P.(1994)Effect of Trinitrotoluene on Microorganisms Appl. Environ. Microbiol. 60 187-194
[8]  
Vorbeck C.(1997)Identification of a Hydride-Meisenheimer Complex as a Metabolite of 2,4,6-Trinitrotoluene by a Mycobacterium Strain Curr. Microbiol. 35 77-83
[9]  
Lenke H.(1974)Catabolism of 3,4,6-Trinitrotoluene by Mycobacterium vaccae Dev. Ind. Microbiol. 15 309-317
[10]  
Fischer P.(1994)Stability of Hydroxylamino-and Aminointermediates from Reduction of 2,4,6-Trinitrotoluene, 2,4-Dinitrotoluene, and 2,6-Dinitrotoluene J. Bacteriol. 176 932-934
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