Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice

被引：0
|
作者：
Tsutomu Sasaki
Osamu Kikuchi
Mayumi Shimpuku
Vina Yanti Susanti
Hiromi Yokota-Hashimoto
Ryo Taguchi
Nobuyuki Shibusawa
Takashi Sato
Lijun Tang
Kosuke Amano
Tomoya Kitazumi
Mitsutaka Kuroko
Yuki Fujita
Jun Maruyama
Yong-soo Lee
Masaki Kobayashi
Takashi Nakagawa
Yasuhiko Minokoshi
Akihiro Harada
Masanobu Yamada
Tadahiro Kitamura
机构：
[1] Gunma University,Metabolic Signal Research Center, Institute for Molecular and Cellular Regulation
[2] Gunma University,Department of Medicine and Molecular Science, Graduate School of Medicine
[3] Gunma University,Laboratory of Molecular Traffic, Department of Molecular and Cellular Biology, Institute for Molecular and Cellular Regulation
[4] National Institute for Physiological Sciences,Division of Endocrinology and Metabolism, Department of Developmental Physiology
[5] University of Toyama,Frontier Research Core for Life Science
[6] Osaka University,Department of Cell Biology, Graduate School of Medicine
来源：
Diabetologia | 2014年 / 57卷
关键词：
AgRP; Brown adipose tissue; Diet-induced obesity; Energy expenditure; Food intake; Hypothalamus; Leptin sensitivity; NAD; POMC; Sympathetic activity;
D O I：
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学科分类号：
摘要：
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页码：819 / 831
页数：12
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