Antitumour activity of transition metal complexes with the thiosemicarbazone derived from 3-acetylumbelliferone

被引:0
作者
Min Wang
Liu-Fang Wang
Yi-Zhi Li
Qin-Xi Li
Zhi-Dong Xu
Dong-Ming Qu
机构
[1] Lanzhou University,National Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering
[2] Hebei University of Science and Technology,undefined
[3] Bethune Military Medical College,undefined
来源
Transition Metal Chemistry | 2001年 / 26卷
关键词
Physical Chemistry; Leukemia; Inorganic Chemistry; Metal Complex; General Formula;
D O I
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中图分类号
学科分类号
摘要
Metal complexes of a new thiosemicarbazone derived from 3-acetylumbelliferone (HL) have been prepared and characterized. The complexes have the general formula ML2 · nH2O where MII = Co, Ni, Cu and Zn; n = 0 and 2. The ligand and its complexes have been studied for their possible antitumour activity against HL-60 human leukemia in vitro.
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页码:307 / 310
页数:3
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