Antitumour activity of transition metal complexes with the thiosemicarbazone derived from 3-acetylumbelliferone

被引:0
作者
Min Wang
Liu-Fang Wang
Yi-Zhi Li
Qin-Xi Li
Zhi-Dong Xu
Dong-Ming Qu
机构
[1] Lanzhou University,National Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering
[2] Hebei University of Science and Technology,undefined
[3] Bethune Military Medical College,undefined
来源
Transition Metal Chemistry | 2001年 / 26卷
关键词
Physical Chemistry; Leukemia; Inorganic Chemistry; Metal Complex; General Formula;
D O I
暂无
中图分类号
学科分类号
摘要
Metal complexes of a new thiosemicarbazone derived from 3-acetylumbelliferone (HL) have been prepared and characterized. The complexes have the general formula ML2 · nH2O where MII = Co, Ni, Cu and Zn; n = 0 and 2. The ligand and its complexes have been studied for their possible antitumour activity against HL-60 human leukemia in vitro.
引用
收藏
页码:307 / 310
页数:3
相关论文
共 62 条
  • [1] Scovill J.P.(1982)undefined J. Med. Chem. 25 1261-undefined
  • [2] Klayman D.L.(1979)undefined J. Med. Chem. 22 1218-undefined
  • [3] Franchino C.F.(1972)undefined Science 178 69-undefined
  • [4] Saryan L.A.(1994)undefined Indian J. Chem. 33A 320-undefined
  • [5] Ankel E.(1994)undefined Transition Met. Chem. 19 195-undefined
  • [6] Krishnamurthy C.(1952)undefined J. Am. Chem. Soc. 18 638-undefined
  • [7] Petering D.H.(1996)undefined Acta Pharmaceutica Sinica 31 434-undefined
  • [8] Elford H.(1971)undefined Coord. Chem. Rev. 7 81-undefined
  • [9] Karon M.(1960)undefined Can. J. Chem. 38 712-undefined
  • [10] Benedict W.F.(1986)undefined Transition Met. Chem. 11 132-undefined