The interplay between the intestinal microbiota and the brain

被引:0
作者
Stephen M. Collins
Michael Surette
Premysl Bercik
机构
[1] Stephen M. Collins,Department of Medicine
[2] Michael Surette and Premysl Bercik are at the Farncombe Family Digestive Health Research Institute,undefined
[3] Faculty of Health Sciences,undefined
[4] McMaster University,undefined
[5] 1200 Main Street West,undefined
[6] Hamilton L8N 3Z5,undefined
[7] Ontario,undefined
[8] Canada.,undefined
来源
Nature Reviews Microbiology | 2012年 / 10卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
A bidirectional neurohumoral communication system known as the gut–brain axis integrates the activities of the intestine and the brain. In this Progress article, Collins, Surette and Bercik describe recent evidence suggesting that the intestinal microbiota is intimately connected with the gut–brain axis and can influence animal behaviour, development and health.
引用
收藏
页码:735 / 742
页数:7
相关论文
共 100 条
  • [1] Qin J(2010)A human gut microbial gene catalogue established by metagenomic sequencing Nature 464 59-65
  • [2] Schiano TD(2010)Treatment options for hepatic encephalopathy Pharmacotherapy 30 S16-S21
  • [3] Wu JC(2012)Psychological co-morbidity in functional gastrointestinal disorders: epidemiology, mechanisms and management J. Neurogastroenterol. Motil. 18 13-18
  • [4] Mayer EA(2011)Gut feelings: the emerging biology of gut–brain communication Nature Rev. Neurosci. 12 453-466
  • [5] Tracey KJ(2009)Reflex control of immunity Nature Rev. Immunol. 9 418-428
  • [6] Mawdsley JE(2005)Psychological stress in IBD: new insights into pathogenic and therapeutic implications Gut 54 1481-1491
  • [7] Rampton DS(2011)The intestinal microbiota and chronic disorders of the gut Nature Rev. Gastroenterol. Hepatol. 8 523-531
  • [8] DuPont AW(2009)The relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease Gastroenterology 136 2003-2014
  • [9] DuPont HL(2008)Microbial endocrinology: how stress influences susceptibility to infection Trends Microbiol. 16 55-64
  • [10] Collins SM(2005)Bacterial cell-to-cell signaling in the gastrointestinal tract Infect. Immun. 73 3197-3209