Microbial colonization influences early B-lineage development in the gut lamina propria

被引：0

作者：

Duane R. Wesemann

Andrew J. Portuguese

Robin M. Meyers

Michael P. Gallagher

Kendra Cluff-Jones

Jennifer M. Magee

Rohit A. Panchakshari

Scott J. Rodig

Thomas B. Kepler

Frederick W. Alt

机构：

[1] Children’s Hospital Boston,Program in Cellular and Molecular Medicine and Department of Medicine

[2] Boston,Department of Genetics

[3] Massachusetts 02115,Division of Rheumatology, Department of Medicine

[4] USA,Department of Pathology

[5] Harvard Medical School,Department of Microbiology

[6] Boston,undefined

[7] Massachusetts 02115,undefined

[8] USA,undefined

[9] Howard Hughes Medical Institute,undefined

[10] Boston,undefined

[11] Massachusetts 02115,undefined

[12] USA,undefined

[13] Immunology and Allergy,undefined

[14] Brigham and Women’s Hospital,undefined

[15] Boston,undefined

[16] Massachusetts 02115,undefined

[17] USA,undefined

[18] Brigham and Women’s Hospital,undefined

[19] Boston,undefined

[20] Massachusetts 02115,undefined

[21] USA,undefined

[22] Boston University School of Medicine,undefined

[23] Boston,undefined

[24] Massachusetts 02215,undefined

[25] USA,undefined

来源：

Nature | 2013年 / 501卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Primary B-cell development is thought to be restricted to the bone marrow; here it is shown to occur also in intestinal tissues of postnatal mice, that it peaks at the time of weaning and is increased upon colonization of germ-free mice, and is thus influenced by commensal microbes.

引用

页码：112 / 115

页数：3

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