A simple and robust model to predict the inhibitory activity of α-glucosidase inhibitors through combined QSAR modeling and molecular docking techniques

被引:0
作者
Elaheh Izadpanah
Siavash Riahi
Zeinab Abbasi-Radmoghaddam
Sajjad Gharaghani
Mohammad Mohammadi-Khanaposhtanai
机构
[1] University of Tehran,College of Engineering, Faculty of Caspian
[2] University of Tehran,Institute of Petroleum Engineering, School of Chemical Engineering, College of Engineering
[3] University of Tehran,Laboratory of Bioinformatics and Drug Design (LBD), Institute of Biochemistry and Biophysics
[4] University of Tehran,College of Engineering, Faculty of Fouman
来源
Molecular Diversity | 2021年 / 25卷
关键词
QSAR; Inhibitory activity; Docking; -Glucosidase; Diabetes; Medicinal chemistry;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1811 / 1825
页数:14
相关论文
共 133 条
  • [11] Narender T(2017)-glucosidase inhibitors with in vivo antidiabetic effect Chem Eng Res Des 120 15-25
  • [12] Madhur G(2017)Discovery of novel J Mol Liq 240 196-208
  • [13] Jaiswal N(2017)-glucosidase inhibitors based on the virtual screening with the homology-modeled protein structure J Mol Liq 225 521-530
  • [14] Agrawal M(2020)Docking and QSAR analysis of tetracyclic oxindole derivatives as Mol Divers 33 388-396
  • [15] Maurya CK(2016)-glucosidase inhibitors J Nat Gas Sci Eng 203 139-150
  • [16] Rahuja N(2018)New novel Chemosphere 16 7185-7192
  • [17] Srivastava AK(2008)-glucosidase inhibitors produced by microbial conversion Bioorg Med Chem 97 118-126
  • [18] Tamrakar AK(2009)Design and synthesis of 2, 6-di (substituted phenyl) thiazolo [3, 2-b]-1, 2, 4-triazoles as Chemom Intell Lab Syst 59 33-44
  • [19] Dinparast L(2016)-glucosidase and J Taiwan Inst Chem Eng 5 231-243
  • [20] Valizadeh H(2000)-amylase inhibitors, co-relative pharmacokinetics and 3D QSAR and risk analysis Mol Divers 43 579-586