The aldehyde dehydrogenase gene superfamily resource center.

被引：0
作者：
Black W. [1 ]
Vasiliou V. [1 ]
机构：
[1] Molecular Toxicology and Environmental Health Sciences Program, Department of Pharmaceutical Sciences, University of Colorado Denver, Aurora, 80045, CO
来源：
Human Genomics | / 4卷 / 2期
基金：
美国国家卫生研究院;
关键词：
Genomic database; aldehyde dehydrogenase; ALDH; nomenclature; gene superfamily;
D O I：
10.1186/1479-7364-4-2-136
中图分类号：
学科分类号：
摘要：
The website www.aldh.org is a publicly available database for nomenclature and functional and molecular sequence information for members of the aldehyde dehydrogenase (ALDH) gene superfamily for animals, plants, fungi and bacteria. The site has organised gene-specific records. It provides synopses of ALDH gene records, marries trivial terms to correct nomenclature and links global accession identifiers with source data. Server-side alignment software characterises the integrity of each sequence relative to the latest genomic assembly and provides identifier-specific detail reports, including a graphical presentation of the transcript's exon-intron structure, its size, coding sequence, genomic strand and locus. Also included are a summary of substrates, inhibitors and enzyme kinetics. The site provides reference lists and is designed to facilitate data mining by interested investigators.
引用
收藏
页码：136 / 142
页数：6
相关论文
共 12 条
  • [1] Maglott D(2007)'Entrez Gene: Gene-centered information at NCBI' Nucleic Acids Res 35 D26-D31
  • [2] Ostell J(2009)'Ensembl 2009' Nucleic Acids Res 37 D690-D697
  • [3] Pruitt KD(2008)'The Mouse Genome Database (MGD): Mouse biology and model systems' Nucleic Acids Res 36 D724-D728
  • [4] Hubbard TJ(1999)'Eukaryotic aldehyde dehydrogenase (ALDH) genes: Human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mapping' Pharmacogenetics 9 421-434
  • [5] Aken BL(undefined)undefined undefined undefined undefined-undefined
  • [6] Ayling S(undefined)undefined undefined undefined undefined-undefined
  • [7] Bult CJ(undefined)undefined undefined undefined undefined-undefined
  • [8] Eppig JT(undefined)undefined undefined undefined undefined-undefined
  • [9] Kadin JA(undefined)undefined undefined undefined undefined-undefined
  • [10] Vasiliou V(undefined)undefined undefined undefined undefined-undefined
12