Cooperativity and biological complexity

被引：0
|
作者：
Adrian Whitty
机构：
[1] Boston University,Adrian Whitty is in the Department of Chemistry
[2] Metcalf Center for Science and Engineering,undefined
[3] 590 Commonwealth Avenue,undefined
[4] Boston,undefined
[5] Massachusetts 02215-2521,undefined
[6] USA. whitty@bu.edu,undefined
来源：
Nature Chemical Biology | 2008年 / 4卷
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摘要：
Cooperative binding effects pervade biology. Only a few basic principles are at play, but in different biological contexts cooperativity appears in distinct guises to achieve different ends. Here I discuss some of the manifestations of cooperativity that are most important in biology and drug discovery as they pertain to systems at different levels of complexity and also highlight aspects of this broadly important phenomenon that remain poorly understood.
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页码：435 / 439
页数：4
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