Clinical profile of severe malaria: Study from a tertiary care center in north India

被引:8
作者
Nandwani S. [1 ]
Pande A. [1 ]
Saluja M. [1 ]
机构
[1] Subharti Institute of Medical Sciences, Meerut, Uttar Pradesh
关键词
Co-infection; Plasmodium falciparum; Plasmodium vivax; Severe malaria;
D O I
10.1007/s12639-012-0208-y
中图分类号
学科分类号
摘要
One hundred and sixty patients having clinical features of severe malaria reported during monsoon season-August-October 2010 at this tertiary care center of north India. Of these 110 (68.75 %) had Plasmodium vivax infection, 30 (18.75 %) were infected with P. falciparum and 20 (12.5 %) had co-infection due to P. vivax and P. falciparum. The diagnosis was made using Rapid Card Test and was confirmed by peripheral smear examination of thick and thin films. Several complications such as acute kidney injury, jaundice, severe anemia, metabolic acidosis, shock, hyperpyrexia, hypoglycemia, generalized tonic-clonic convulsions etc. were found to be more prevalent in patients with P. vivax infection. These symptoms were until recently known to be associated with falciparum malaria. © 2012 Indian Society for Parasitology.
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页码:11 / 15
页数:4
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共 27 条
  • [1] Beg M.A., Khan R., Baig S.M., Gulzar Z., Hussain R., Smego R.A., Cerebral involvement in benign tertian malaria, Am J Trop Med Hyg, 67, pp. 230-232, (2002)
  • [2] Chakravarty A., Ghosh B., Bhattacharyya R., Sengupta S., Mukherjee S., Acute inflammatory demyelinating polyneuropathy following Plasmodium vivax malaria, Neurol India, 52, pp. 130-131, (2004)
  • [3] Clark I.A., Cowden W.B., Why is the pathology of falciparum worse than that of vivax malaria, Parasitol Today, 15, pp. 458-461, (1999)
  • [4] Dhingra N., Jha P., Sharma V.P., Et al., For the Million Death Study Collaborators (2010) Adult and child malaria mortality in India: a nationally representative mortality survey, Lancet, 376, pp. 1768-1774
  • [5] Diamond-Smith N., Singh N., Gupta R.K., Et al., Estimating the burden of malaria in pregnancy: a case study from rural Madhya Pradesh, India, Malar J, 8, (2009)
  • [6] Genton B., D'Acremont V., Rare L., Baea K., Reeder J.C., Alpers M.P., Muller I., Plasmodium vivax and mixed infections are associated with severe malaria in children: a prospective cohort study from Papua New Guinea, PLoS Med, 5, pp. 1-9, (2008)
  • [7] Habib A.G., Singh K.S., Respiratory distress in non-immune adults with imported malaria, Infection, 32, pp. 356-359, (2004)
  • [8] Jayavanth S., Park B.C., Microrheologic dysfunctions in blood during malaria, Indian J Exp Biol, 45, pp. 111-120, (2007)
  • [9] Kochar D.K., Agarwal R.P., Kochar S.K., Jain R., Rawat N., Pokharna R.K., Kachhawaha S., Srivastava T., Hepatocyte dysfunction and hepatic encephalopathy in Plasmodium falciparum malaria, Qjm, 96, pp. 505-512, (2003)
  • [10] Kochar D.K., Singh P., Agarwal P., Kochar S.K., Pokharna R., Sareen P.K., Malarial hepatitis, J Assoc Physicians India, 51, pp. 1069-1072, (2003)