Intravenous immunoglobulin in neurological disorders: a mechanistic perspective

被引：0
作者：
Namita Misra
Jagadeesh Bayry
Amal Ephrem
Suryasarathi Dasgupta
Sandrine Delignat
Jean-Paul Duong Van Huyen
Fabienne Prost
Sebastien Lacroix-Desmazes
Antonino Nicoletti
Michel D. Kazatchkine
Srini V. Kaveri
机构：
[1] INSERM U681,
[2] Institut des Cordeliers,undefined
[3] INSERM U681 and Université Pierre et Marie Curie Institut des Cordeliers,undefined
来源：
Journal of Neurology | 2005年 / 252卷
关键词：
intravenous immunoglobulin; neurological disorders; mechanisms;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Intravenous immunoglobulin (IVIg) has been used in the treatment of primary and secondary antibody deficiencies for over 25 years. It is a safe preparation with no long-term side effects. IVIg was first demonstrated to be effective in autoimmune disorders, two decades ago, in the treatment of acute immune thrombocytopenia. Since then, the therapeutic efficacy of IVIg has been established in Guillain Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP),myasthenia gravis (MG), dermatomyositis (DM), Kawasaki syndrome and the prevention of graft-versus-host disease in recipients of allogeneic bone marrow transplants and reported in a large number of other autoimmune and systemic inflammatory conditions.
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页码：i1 / i6
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