Anti-microbial benzimidazole derivatives: synthesis and in vitro biological evaluation

被引：0
|
作者：
Love Kumar Soni
Tamanna Narsinghani
Anand Sethi
机构：
[1] Devi Ahilya University,Pharmaceutical & Medicinal Chemistry Research Lab., School of Pharmacy
[2] Takshashila Campus,undefined
来源：
Medicinal Chemistry Research | 2012年 / 21卷
关键词：
2-Styryl benzimidazole; Anti-microbial activity; Anti-bacterial activity; Anti-fungal activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In this study, we have synthesized 5-(nitro/chloro)-2-styryl-benzimidazoles and evaluated for in vitro anti-microbial activity with different strain like anti-bacterial activity against Staphylococcus aureus, Escherichia coli, and anti-fungal activity against Candida albicans were carried out. Compounds 2, 4, 7, 8 showed higher activity against S. aureus, compounds 2, 8, 9, 10 showed higher activity against E. coli and Compounds 2, 7, 9, 8 showed higher activity against C. albicans.
引用
收藏
页码：4330 / 4334
页数：4
相关论文
共 50 条
  • [41] Synthesis and biological evaluation of 5-substituted derivatives of benzimidazole
    Vasic, Vesna P.
    Penjisevic, Jelena Z.
    Novakovic, Irena T.
    Sukalovic, Vladimir V.
    Andric, Deana B.
    Kostic-Rajacic, Sladana V.
    JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2014, 79 (03) : 277 - 282
  • [42] Synthesis, Characterization, and Biological Evaluation of Benzimidazole Derivatives as Potential Anxiolytics
    Nannapaneni, D. T.
    Atyam, Gupta V. S. S. S.
    Reddy, M., I
    Raidu, Sarva Ch
    JOURNAL OF YOUNG PHARMACISTS, 2010, 2 (03) : 273 - 279
  • [43] Synthesis and biological evaluation of 2-substituted benzimidazole derivatives
    Mariappan, Gurusamy
    Hazarika, Rajib
    Alam, Faruk
    Karki, Rashmi
    Patangia, Uddhav
    Nath, Shyamalendu
    ARABIAN JOURNAL OF CHEMISTRY, 2015, 8 (05) : 715 - 719
  • [44] In vitro evaluation of anti-microbial activity of erbium YAG laser.
    Rebiscini, P.
    Caramia, L.
    Quaranta, A.
    Scrascia, A.
    Casaglia, A.
    Cerroni, L.
    D'Addona, A.
    JOURNAL OF DENTAL RESEARCH, 2003, 82 : B281 - B281
  • [45] In vitro Evaluation of Anti-Microbial Potential of the Leaf Extracts of Acacia modesta
    Zafar, Salman
    Khan, Aziz
    Parveen, Zahida
    Khan, Momin
    Khan, Kamin
    JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, 2014, 36 (06): : 1105 - 1108
  • [46] New Diclofenac Derivatives as Anti-Microbial, Anti-Inflammatory Agents: Design, Synthesis, Biological Screening, and Molecular Docking Study
    Adel M. Kamal Mahmoud M. Hamed
    Shawkat A. El-Dean
    Mahmoud S. Abdel-Mohsen
    Russian Journal of Bioorganic Chemistry, 2021, 47 : 208 - 220
  • [47] New Diclofenac Derivatives as Anti-Microbial, Anti-Inflammatory Agents: Design, Synthesis, Biological Screening, and Molecular Docking Study
    Hamed, Mahmoud M.
    El-Dean, Adel M. Kamal
    Abdel-Mohsen, Shawkat A.
    Tolba, Mahmoud S.
    RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2021, 47 (01) : 208 - 220
  • [48] Synthesis, anti-microbial and anti-inflammatory activities of 18β-glycyrrhetinic acid derivatives
    Yang, Yang
    Zhu, Qiuyan
    Zhong, Yingying
    Cui, Xiping
    Jiang, Zhengyun
    Wu, Panpan
    Zheng, Xi
    Zhang, Kun
    Zhao, Suqing
    BIOORGANIC CHEMISTRY, 2020, 101
  • [49] Graph Theoretical Analysis, In Silico Modeling, Synthesis, Anti-Microbial and Anti-TB Evaluation of Novel Quinoxaline Derivatives
    Saravanan, Govindaraj
    Selvam, Theivendren Panneer
    Alagarsamy, Veerachamy
    Kunjiappan, Selvaraj
    Joshi, Shrinivas D.
    Indhumathy, Murugan
    Kumar, Pandurangan Dinesh
    DRUG RESEARCH, 2018, 68 (05) : 250 - 262
  • [50] Synthesis, anti-microbial and anti-cancer evaluation study of 3-(3-benzofuranyl)-coumarin derivatives
    Chougala, Bahubali M.
    Shastri, Samundeeswari L.
    Holiyachi, Megharaja
    Shastri, Lokesh A.
    More, Sunil S.
    Ramesh, K. V.
    MEDICINAL CHEMISTRY RESEARCH, 2015, 24 (12) : 4128 - 4138
12345