Anti-microbial benzimidazole derivatives: synthesis and in vitro biological evaluation

被引:0
|
作者
Love Kumar Soni
Tamanna Narsinghani
Anand Sethi
机构
[1] Devi Ahilya University,Pharmaceutical & Medicinal Chemistry Research Lab., School of Pharmacy
[2] Takshashila Campus,undefined
来源
关键词
2-Styryl benzimidazole; Anti-microbial activity; Anti-bacterial activity; Anti-fungal activity;
D O I
暂无
中图分类号
学科分类号
摘要
In this study, we have synthesized 5-(nitro/chloro)-2-styryl-benzimidazoles and evaluated for in vitro anti-microbial activity with different strain like anti-bacterial activity against Staphylococcus aureus, Escherichia coli, and anti-fungal activity against Candida albicans were carried out. Compounds 2, 4, 7, 8 showed higher activity against S. aureus, compounds 2, 8, 9, 10 showed higher activity against E. coli and Compounds 2, 7, 9, 8 showed higher activity against C. albicans.
引用
收藏
页码:4330 / 4334
页数:4
相关论文
共 50 条
  • [21] SYNTHESIS OF ANTI-MICROBIAL AGENTS .3. SYNTHESIS AND ANTI-MICROBIAL ACTIVITIES OF THIAZOLO[5,4-B]NAPHTHYRIDINE DERIVATIVES
    SUZUKI, N
    DOHMORI, R
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1979, 27 (02) : 410 - 418
  • [22] SYNTHESIS AND ANTI-MICROBIAL EVALUATION OF SOME NOVEL 1,2,4-TRIAZOLE DERIVATIVES
    Upmanyu, Neeraj
    Kumar, Sanjay
    Kharya, Murali-Dhar
    Shah, Kamal
    Mishra, Praadep
    ACTA POLONIAE PHARMACEUTICA, 2011, 68 (02): : 213 - 221
  • [23] Synthesis and anti-microbial evaluation with in silico studies of novel 2-aminothiazole benzohydrazide derivatives
    Amrutha, S.
    Das, Paramita
    Nayak, Anjali
    Laha, Supratip
    Begum, Sharmina
    Bhardwaj, Sakshi
    FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES, 2025, 11 (01)
  • [24] DIHYDROXYBENZENE DERIVATIVES OF ANTI-MICROBIAL ACTIVITY
    BADAWI, A
    ELMAGHRABY, A
    HAROUN, B
    SOLIMAN, H
    PHARMAZIE, 1980, 35 (12): : 748 - 751
  • [25] Synthesis and biological evaluation of 2-aminoimidazole/carbamate hybrid anti-biofilm and anti-microbial agents
    Rogers, Steven A.
    Lindsey, Erick A.
    Whitehead, Daniel C.
    Mullikin, Trey
    Melander, Christian
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (04) : 1257 - 1260
  • [26] Synthesis and biological evaluation of some thio containing pyrrolo [2,3-d] Pyrimidine derivatives for their anti-inflammatory and anti-microbial activities
    Mohamed, Mosaad S.
    Kamel, Rehab
    Fatahala, Samar S.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (07) : 2994 - 3004
  • [28] Synthesis, in-vitro Microbial and Cytotoxic Studies of New Benzimidazole Derivatives
    Harisha, Reddy S.
    Hosamani, Kallappa M.
    Keri, Rangappa S.
    ARCHIV DER PHARMAZIE, 2009, 342 (07) : 412 - 419
  • [29] Synthesis, biological evaluation, density functional calculation and molecular docking analysis of novel spiropyrrolizidines derivatives as potential anti-microbial and anti-coagulant agents
    Askri, Sonia
    Edziri, Hayet
    Ben Hamouda, Manel
    Mchiri, Chadlia
    Gharbi, Rafik
    Abd El-Gawad, Hala H.
    El-Tahawy, Mohsen M. T.
    JOURNAL OF MOLECULAR STRUCTURE, 2022, 1250
  • [30] Design, Synthesis, Biological Evaluation and Molecular Modeling Study of Novel Indolizine-1-Carbonitrile Derivatives as Potential Anti-Microbial Agents
    Faghih-Mirzaei, Ehsan
    Seifi, Mohammad
    Abaszadeh, Mehdi
    Zomorodian, Kamiar
    Helali, Helia
    IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2018, 17 (03): : 883 - 895