Visualization of arrestin recruitment by a G-protein-coupled receptor

被引:0
|
作者
Arun K. Shukla
Gerwin H. Westfield
Kunhong Xiao
Rosana I. Reis
Li-Yin Huang
Prachi Tripathi-Shukla
Jiang Qian
Sheng Li
Adi Blanc
Austin N. Oleskie
Anne M. Dosey
Min Su
Cui-Rong Liang
Ling-Ling Gu
Jin-Ming Shan
Xin Chen
Rachel Hanna
Minjung Choi
Xiao Jie Yao
Bjoern U. Klink
Alem W. Kahsai
Sachdev S. Sidhu
Shohei Koide
Pawel A. Penczek
Anthony A. Kossiakoff
Virgil L. Woods Jr
Brian K. Kobilka
Georgios Skiniotis
Robert J. Lefkowitz
机构
[1] Duke University Medical Center,Department of Medicine
[2] University of Michigan Medical School,Life Sciences Institute and Department of Biological Chemistry
[3] University of California at San Diego,Department of Chemistry
[4] School of Pharmaceutical & Life Sciences,Department of Biochemistry
[5] Changzhou University,Department of Biochemistry and Molecular Biology
[6] Changzhou,Department of Biochemistry and Molecular Biology
[7] Jiangsu 213164,Department of Molecular and Cellular Physiology
[8] China,undefined
[9] Terrence Donnelly Centre for Cellular and Biomolecular Research,undefined
[10] University of Toronto,undefined
[11] Toronto,undefined
[12] Ontario M5S 3E1,undefined
[13] Canada,undefined
[14] Duke University Medical Center,undefined
[15] University of Chicago,undefined
[16] The University of Texas Medical School at Houston,undefined
[17] Stanford University School of Medicine,undefined
[18] 279 Campus Drive,undefined
[19] Howard Hughes Medical Institute,undefined
[20] Duke University Medical Center,undefined
[21] Present address: Department of Biological Sciences and Bioengineering,undefined
[22] Indian Institute of Technology,undefined
[23] Kanpur 208016,undefined
[24] India.,undefined
来源
Nature | 2014年 / 512卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Single-particle electron microscopy and hydrogen–deuterium exchange mass spectrometry are used to characterize the structure and dynamics of a G-protein-coupled receptor–arrestin complex.
引用
收藏
页码:218 / 222
页数:4
相关论文
共 50 条
  • [21] G-protein-coupled receptor deorphanizations
    Saito, Y
    Civelli, O
    INTERNATIONAL REVIEW OF NEUROBIOLOGY, VOL 65, 2005, 65 : 179 - 209
  • [22] G-PROTEIN-COUPLED RECEPTOR KINASES
    LEFKOWITZ, RJ
    FASEB JOURNAL, 1994, 8 (07): : A1377 - A1377
  • [23] Folding of a G-protein-coupled receptor
    Robson, A
    Booth, PJ
    BIOPHYSICAL JOURNAL, 2004, 86 (01) : 254A - 254A
  • [24] G-protein-coupled receptor microarrays
    Fang, Y
    Frutos, AG
    Lahiri, J
    CHEMBIOCHEM, 2002, 3 (10) : 987 - 991
  • [25] ARRESTIN BINDING DETERMINES THE RATE OF INACTIVATION OF THE G-PROTEIN-COUPLED RECEPTOR RHODOPSIN IN-VIVO
    RANGANATHAN, R
    STEVENS, CF
    CELL, 1995, 81 (06) : 841 - 848
  • [26] Application of G Protein-Coupled Receptor-Heteromer Identification Technology to Monitor β-Arrestin Recruitment to G Protein-Coupled Receptor Heteromers
    See, Heng B.
    Seeber, Ruth M.
    Kocan, Martina
    Eidne, Karin A.
    Pfleger, Kevin D. G.
    ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES, 2011, 9 (01) : 21 - 30
  • [27] Role of Phosphoserine and Phosphothreonine for binding of arrestin to G-protein-coupled receptors
    Moesslein, N.
    Buenemann, M.
    Krasel, C.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2017, 390 : S26 - S27
  • [28] Conformational signatures in β-arrestin2 reveal natural biased agonism at a G-protein-coupled receptor
    Reyes-Alcaraz, Arfaxad
    Lee, Yoo-Na
    Yun, Seongsik
    Hwang, Jong-Ik
    Seong, Jae Young
    COMMUNICATIONS BIOLOGY, 2018, 1
  • [29] Conformational signatures in β-arrestin2 reveal natural biased agonism at a G-protein-coupled receptor
    Arfaxad Reyes-Alcaraz
    Yoo-Na Lee
    Seongsik Yun
    Jong-Ik Hwang
    Jae Young Seong
    Communications Biology, 1
  • [30] GIP, a G-protein-coupled receptor interacting protein
    Innamorati, G
    Whang, MI
    Molteni, R
    Le Gouill, C
    Birnbaumer, M
    REGULATORY PEPTIDES, 2002, 109 (1-3) : 173 - 179