Expression of ghrelin in fundus is increased after gastric banding in morbidly obese patients

被引:0
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作者
Bernard Uzzan
Jean-Marc Catheline
Christine Lagorce
Gheorghe Airinei
Cyriaque Bon
Régis Cohen
Gérard-Yves Perret
Thomas Aparicio
Robert Benamouzig
机构
[1] Hôpital Avicenne,Department of Pharmacology
[2] Assistance Publique — Hôpitaux de Paris,Hormonology
[3] Hôpital Avicenne,Bariatric Surgical College
[4] Assistance Publique — Hôpitaux de Paris,Department of Pathology
[5] Hôpital Avicenne,Department of Gastroenterology
[6] Assistance Publique — Hôpitaux de Paris,Department of Gastroenterology
[7] Hôpital Avicenne,Service de Chirurgie Générale et Digestive
[8] Assistance Publique — Hôpitaux de Paris,undefined
[9] Hôpital Bichat,undefined
[10] Assistance Publique — Hôpitaux de Paris,undefined
[11] Hôpital Avicenne,undefined
来源
Obesity Surgery | 2007年 / 17卷
关键词
Ghrelin; fundus; morbid obesity; bariatric surgery; gastric banding;
D O I
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中图分类号
学科分类号
摘要
Background: Ghrelin, a 28 amino-acid acylated orexigenic peptide secreted by the stomach, acts on the hypothalamic arcuate nucleus which stimulates feeding behavior. Serum ghrelin level increases during fasting and decreases after a meal. Serum ghrelin is low in obese patients. Whether ghrelin is implicated in weight loss in obese patients after laparoscopic adjustable gastric banding (LAGB) is still debated. In this study, we assessed serum ghrelin level and gastric fundus expression before and 1 year after LAGB.
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页码:1159 / 1164
页数:5
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