Rhino-orbito-cerebral Mucormycosis: Pictorial Review

被引:0
作者
Vivek Pai
Rima Sansi
Ritesh Kharche
Sridevi Chaitanya Bandili
Bhujang Pai
机构
[1] SevenHills Hospital,Department of Radiology
[2] SevenHills Hospital,Department of Histopathology
[3] SevenHills Hospital,Department of Microbiology
来源
Insights into Imaging | / 12卷
关键词
Mucormycosis; Rhino-orbito-cerebral Mucormycosis; Invasive fungal sinusitis;
D O I
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中图分类号
学科分类号
摘要
Mucormycosis (MCR) is a fulminant, potentially lethal, opportunistic fungal infection. Diabetes, immunocompromised states and elevated serum iron levels are the most important risk factors for contracting MCR infection. Recently, MCR co-infections have been observed in patients with COVID-19 disease owing to a complex interplay of metabolic factors and corticosteroid therapy. Rhino-orbito-cerebral mucormycosis (ROCM) is the most common clinical form of MCR infection and refers to infection of the nasal cavities, paranasal sinuses, neck spaces, orbits and intracranial structures. Sinonasal inoculation is typically the primary site of infection; the necrotising and angioinvasive properties of the fungus facilitate its spread into adjacent structures. In this review, we discuss the pertinent mycology and risk factors of MCR infection. The review also aims to acquaint the reader with the cross-sectional imaging appearances of ROCM and its complications. All the cases discussed in this pictorial essay are microbiologically and/or histopathologically proven cases of ROCM with concomitant COVID-19 infection.
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