A systematic review and meta-analysis for the adverse effects, immunogenicity and efficacy of Lyme disease vaccines: Guiding novel vaccine development

被引:0
作者
Alaa Badawi
Maria Shering
Shusmita Rahman
L. Robbin Lindsay
机构
[1] Public Health Agency of Canada,Public Health Risk Science Division, National Microbiology Laboratory
[2] University of Toronto,Faculty of Arts and Science
[3] University of Toronto,Dalla Lana School of Public Health
[4] Public Health Agency of Canada,National Microbiology Laboratory
来源
Canadian Journal of Public Health | 2017年 / 108卷
关键词
Lyme disease; vaccine; clinical trial; efficacy; systematic review; maladie de Lyme; vaccin; essai clinique; efficacité potentielle; revue systématique;
D O I
暂无
中图分类号
学科分类号
摘要
BACKGROUND: Lyme borreliosis (LB) is the most prevalent arthropod-borne infectious disease in North America. Currently, no vaccine is available to prevent LB in humans, although monovalent and multivalent vaccines have been developed in the past.
引用
收藏
页码:e62 / e70
相关论文
共 169 条
[1]  
Little SE(2010)Lyme borreliosis in dogs and humans in the USA Trends Parasitai 26 213-18
[2]  
Heise SR(2015)The increasing risk of Lyme disease in Canada Can Vet J 56 693-99
[3]  
Blagburn BL(1995)Survival and development of J Med Entamol 32 143-52
[4]  
Callister SM(1993) (Acari: Ixodidae) under various climatic conditions in Ontario, Canada Lancet 342 1096-99
[5]  
Mead PS(2014)Health and climate change: Biodiversity Can Commun Dis Rep 40 74-82
[6]  
Bouchard C(2015)Environmental risk from Lyme disease in central and eastern Canada: A summary of recent surveillance information Folia Biologica 63 159-65
[7]  
Leonard E(1998)Why is there still no human vaccine against Lyme borreliosis? N Eng J Med 339 216-22
[8]  
Koffi JK(1998)A vaccine consisting of recombinant N Eng J Med 339 209-15
[9]  
Pelcat Y(1994) outer-surface protein A to prevent Lyme disease JAMA 271 1764-68
[10]  
Peregrine A(2011)Vaccination against Lyme disease with recombinant Clin Infect Dis 52 s253-58