Next-Generation Sequencing in the Mycology Lab

被引：32
作者：
Zoll J. [1 ]
Snelders E. [2 ]
Verweij P.E. [1 ]
Melchers W.J.G. [1 ]
机构：
[1] Department of Medical Microbiology, Radboud University Medical Centre, Box 9101, Nijmegen
[2] Institut Pasteur, Unité de Mycologie Moléculaire, Paris
来源：
Current Fungal Infection Reports | 2016年 / 10卷 / 2期
关键词：
Clinical mycology lab issues; Mycobiome; Next-generation sequencing; Resistance; Review; Whole genome sequencing;
D O I：
10.1007/s12281-016-0253-6
中图分类号：
学科分类号：
摘要：
New state-of-the-art techniques in sequencing offer valuable tools in both detection of mycobiota and in understanding of the molecular mechanisms of resistance against antifungal compounds and virulence. Introduction of new sequencing platform with enhanced capacity and a reduction in costs for sequence analysis provides a potential powerful tool in mycological diagnosis and research. In this review, we summarize the applications of next-generation sequencing techniques in mycology. © 2016, The Author(s).
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页码：37 / 42
页数：5
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