G protein-coupled estrogen receptor 1 (GPER-1) and agonist G-1 inhibit growth of ovarian cancer cells by activation of anti-tumoral transcriptome responses: impact of GPER-1 mRNA on survival

被引：0
作者：
Susanne Schüler-Toprak
Maciej Skrzypczak
Tanja Ignatov
Atanas Ignatov
Olaf Ortmann
Oliver Treeck
机构：
[1] University Medical Center Regensburg,Department of Obstetrics and Gynecology, Laboratory for Molecular Oncology
[2] Medical University of Lublin,Second Department of Gynecology
来源：
Journal of Cancer Research and Clinical Oncology | 2020年 / 146卷
关键词：
G-protein-coupled estrogen receptor; Ovarian cancer; DNA microarray; G-1;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：3175 / 3188
页数：13
相关论文
共 39 条
  • [21] Aberrant Ligand-Induced Activation of G Protein-Coupled Estrogen Receptor 1 (GPER) Results in Developmental Malformations During Vertebrate Embryogenesis
    Jayasinghe, B. Sumith
    Volz, David C.
    TOXICOLOGICAL SCIENCES, 2012, 125 (01) : 262 - 273
  • [22] Oxidative/antioxidative enzyme-mediated antiproliferative and proapoptotic effects of the GPER1 agonist G-1 on lung cancer cells
    Kurt, Akif Hakan
    Celik, Ahmet
    Kelleci, Bekir Mehmet
    ONCOLOGY LETTERS, 2015, 10 (05) : 3177 - 3182
  • [23] G protein-coupled estrogen receptor (GPER) selective agonist G1 attenuates the neurobehavioral, molecular and biochemical alterations induced in a valproic acid rat model of autism
    Hameed, Rehab Abdel
    Ahmed, Emad K.
    Mahmoud, Asmaa A.
    Atef, Azza A.
    LIFE SCIENCES, 2023, 328
  • [24] The environmental hormone nonylphenol interferes with the therapeutic effects of G protein-coupled estrogen receptor specific agonist G-1 on murine allergic rhinitis
    Wang, Yun-xiu
    Gu, Zhao-wei
    Hao, Li-ying
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2020, 78
  • [25] The G protein-coupled oestrogen receptor 1 agonist G-1 disrupts endothelial cell microtubule structure in a receptor-independent manner
    Holm, Anders
    Grande, Per-Olof
    Luduena, Richard F.
    Olde, Bjorn
    Prasad, Veena
    Leeb-Lundberg, L. M. Fredrik
    Nilsson, Bengt-Olof
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2012, 366 (1-2) : 239 - 249
  • [26] The G protein-coupled oestrogen receptor 1 agonist G-1 disrupts endothelial cell microtubule structure in a receptor-independent manner
    Anders Holm
    Per-Olof Grände
    Richard F. Ludueña
    Björn Olde
    Veena Prasad
    L. M. Fredrik Leeb-Lundberg
    Bengt-Olof Nilsson
    Molecular and Cellular Biochemistry, 2012, 366 : 239 - 249
  • [27] The G-Protein-Coupled Estrogen Receptor Selective Agonist G-1 Attenuates Cell Viability and Migration in High-Grade Serous Ovarian Cancer Cell Lines
    Hanafi, Donia
    Onyenwoke, Rob U.
    Kimbro, K. Sean
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (12)
  • [28] The G-Protein-Coupled Estrogen Receptor Agonist G-1 Mediates Antitumor Effects by Activating Apoptosis Pathways and Regulating Migration and Invasion in Cervical Cancer Cells
    Gaxiola-Rubio, Abigail
    Jave-Suarez, Luis Felipe
    Hernandez-Silva, Christian David
    Ramirez-de-Arellano, Adrian
    Villegas-Pineda, Julio Cesar
    de Jesus Lizarraga-Ledesma, Marisa
    Ramos-Solano, Moises
    Diaz-Palomera, Carlos Daniel
    Pereira-Suarez, Ana Laura
    CANCERS, 2024, 16 (19)
  • [29] G protein-coupled estrogen receptor-1 agonist induces chemotherapeutic effect via ER stress signaling in gastric cancer
    Lee, Seon-Jin
    Kim, Tae Woo
    Park, Gyeong Lim
    Hwang, Yo Sep
    Cho, Hee Jun
    Kim, Jong-Tae
    Lee, Hee Gu
    BMB REPORTS, 2019, 52 (11) : 647 - 652
  • [30] G protein-coupled estrogen receptor selective agonist, G1, improves the molecular and biochemical markers in a cisplatin mouse model of CKD*
    Ahmed, Hala A.
    Shaaban, Ahmed A.
    Makled, Mirhan N.
    Ibrahim, Tarek M.
    CHEMICO-BIOLOGICAL INTERACTIONS, 2024, 398
1234