Venous Thromboembolism in the Elderly

被引：3

作者：

Ali M.S. ^{[1
]}

Czarnecka-Kujawa K. ^{[2
]}

机构：

[1] Department of Internal Medicine, John H. Stroger, Jr. Hospital of Cook County, 1900 West Polk St, 15th Floor, Chicago, 60612, IL

[2] Division of Respirology, Division of Thoracic Surgery, Toronto General Hospital, University Health Network, University of Toronto, 585 University Ave. 9N 941, Toronto, M5G 2N2, ON

来源：

Current Geriatrics Reports | 2016年 / 5卷 / 2期

关键词：

Apixiban; Cancer; Compression stockings; Computerized tomographic angiography; Contrast-induced nephropathy; D-dimer; Dabigatran; Deep venous thrombosis; Geriatrics; Inferior vena cava filter; Low-molecular-weight heparin; Novel oral anticoagulants; Postthrombotic syndrome; Pulmonary embolism; Rivaroxaban; Thrombolysis; Ultrasonography; Unfractionated heparin; Venous thromboembolism; Warfarin; Wells Score;

D O I：

10.1007/s13670-016-0163-z

中图分类号：

学科分类号：

摘要：

Aging is a major risk factor for venous thromboembolism. Compared to the general population, the elderly have a much higher 1-year mortality from venous thromboembolism (VTE). Clinical presentation of VTE in the elderly tends to be different, with atypical symptoms being more common than in the general population. Diagnostic work-up starts with establishing a VTE pretest probability followed by D-dimer testing for patients with low pretest probability and confirmatory testing for patients with high pretest probability of VTE. The age-adjusted D-dimer cutoffs are associated with a higher specificity without compromising the test’s sensitivity. Anticoagulation is the cornerstone of VTE therapy. The use of novel oral anticoagulants is safe in elderly patients and is associated with a decreased risk of bleeding. © 2016, Springer Science+Business Media New York.

引用

页码：132 / 139

页数：7

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