Synthesis, Structure, and Antiradical Activity of New Methano[1,3]Thiazolo[2,3-d][1,3,5]Benzoxa-Diazocine Derivatives

被引：0

作者：

I. V. Kulakov

S. A. Talipov

Z. T. Shulgau

T. M. Seilkhanov

机构：

[1] Omsk F. M. Dostoevskii State University,

[2] Institute of Bioorganic Chemistry,undefined

[3] Center for Life Sciences,undefined

[4] Inc.,undefined

[5] Sh. Ualikhanov Kokshetau State University,undefined

来源：

Chemistry of Heterocyclic Compounds | 2015年 / 50卷

关键词：

2; -2,6-methano[1,3,5]benzoxadiazocines; salicylic aldehyde; thiourea; Biginelli reaction; intramolecular heterocyclization; X-ray structural analysis;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The reaction of 2,6-methano[1, 3, 5]benzoxadiazocines, obtained in Biginelli reaction, with chloroacetic acid derivatives produced previously unknown tricyclic methano[1,3]thiazolo[2,3-d][1,3,5]benz-oxadiazocines, the structure of which was proved by 1Н NMR spectroscopy and X-ray structural analysis. The methano[1,3]thiazolo[2,3-d][1,3,5]benzoxadiazocines showed no antiradical activity in contrast to the starting 2,6-methano[1,3,5]benzoxadiazocines.

引用

页码：1478 / 1486

页数：8

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