Synthesis, Structure, and Antiradical Activity of New Methano[1,3]Thiazolo[2,3-d][1,3,5]Benzoxa-Diazocine Derivatives

被引：0
|
作者：
I. V. Kulakov
S. A. Talipov
Z. T. Shulgau
T. M. Seilkhanov
机构：
[1] Omsk F. M. Dostoevskii State University,
[2] Institute of Bioorganic Chemistry,undefined
[3] Center for Life Sciences,undefined
[4] Inc.,undefined
[5] Sh. Ualikhanov Kokshetau State University,undefined
来源：
Chemistry of Heterocyclic Compounds | 2015年 / 50卷
关键词：
2; -2,6-methano[1,3,5]benzoxadiazocines; salicylic aldehyde; thiourea; Biginelli reaction; intramolecular heterocyclization; X-ray structural analysis;
D O I：
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学科分类号：
摘要：
The reaction of 2,6-methano[1, 3, 5]benzoxadiazocines, obtained in Biginelli reaction, with chloroacetic acid derivatives produced previously unknown tricyclic methano[1,3]thiazolo[2,3-d][1,3,5]benz-oxadiazocines, the structure of which was proved by 1Н NMR spectroscopy and X-ray structural analysis. The methano[1,3]thiazolo[2,3-d][1,3,5]benzoxadiazocines showed no antiradical activity in contrast to the starting 2,6-methano[1,3,5]benzoxadiazocines.
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页码：1478 / 1486
页数：8
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