Angiosonography in suspicious breast lesions with non-diagnostic FNAC: Comparison with Power Doppler US

被引：6

作者：

Caumo F. ^{[1
]}

Carbognin G. ^{[1
]}

Casarin A. ^{[1
]}

Pinali L. ^{[1
]}

Vasori S. ^{[1
]}

D'Onofrio M. ^{[1
]}

Mucelli R.P. ^{[1
]}

机构：

[1] Sezione di Radiologia, Dipartimento di Scienze Morfologico-Biomediche, Azienda Ospedaliera Policlinico G.B. Rossi, I-37134 Verona

来源：

La radiologia medica | 2006年 / 111卷 / 1期

关键词：

Angiosonography; Breast focal lesions; Breast; neoplastic lesions; Power Doppler US;

D O I：

10.1007/s11547-006-0007-6

中图分类号：

学科分类号：

摘要：

Purpose. The purpose of this study was to evaluate the accuracy of angiosonography in comparison with colour Doppler ultrasound (US) in the discrimination of suspicious breast lesions with non-diagnostic fine-needle aspiration cytology (FNAC). Materials and methods. Pre-operative Power Doppler US and angiosonography were prospectively performed in 20 suspicious breast lesions with non-diagnostic FNAC. A second-generation US contrast agent was utilised with a high-frequency transducer and a contrast-specific algorithm (low acoustic pressure CnTI). The enhancement characteristics of all lesions were analysed using qualitative and quantitative parameters obtained from time-intensity curves with the different imaging modalities. The final diagnosis was confirmed at pathology in all cases. Microvessel density (MVD) was assessed in the surgical specimen using CD34. Results. The correct assessment of biological behaviour was achieved in all cases by angiosonography (sensitivity of 100%; specificity of 91%) and colour Doppler US (45% sensitivity; 78% specificity). MVD correlated with the biological behaviour. Conclusions. Angiosonography is more accurate than colour Doppler US in the correct assessment of biological behaviour of suspicious breast lesions.

引用

页码：61 / 72

页数：11

共 30 条

[1]

Folkman J., Klagsbrunn M., Angiogenetic factors, Science, 235, pp. 442-447, (1987)

[2]

Weidner N., Semple J., Welch W.R., Folkman J., Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma, New Engl J Med, 324, pp. 1-8, (1991)

[3]

Horak E.R., Leek R., Klenk N., Et al., Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer, Lancet, 340, pp. 1120-1124, (1992)

[4]

Rizzatto G., Towards a more sophisticated use of breast ultrasound, Eur Radiol, 11, pp. 2425-2435, (2001)

[5]

Correas J.M., Bridal L., Lesavre A., Et al., Ultrasound contrast agents: Properties, principles of action, tolerance and artifacts, Eur Radiol, 11, pp. 1316-1328, (2001)

[6]

Guazzaroni M., Perretta T., Cecconi P., Et al., Mezzi di contrasto in senologia, Radiol Med, 107, pp. 75-82, (2004)

[7]

Mehta T.S., Current use of ultrasound in the evaluation of the breast, Radiol Clin N Am, 41, pp. 841-856, (2003)

[8]

Maresca G., Summaria V., Colagrande C., Et al., New prospects for ultrasound contrast agents, Eur J Radiol, 27, SUPPL. 2, (1998)

[9]

Hook S.H., Kwang H.J., Value of contrast-enhanced power Doppler sonography using a microbubble echoenhancing agent in evaluation of small breast lesions, J Clin Ultrasound, 31, pp. 227-238, (2003)

[10]

Huber S., Helbich T., Kettenbach J., Et al., Effect of a microbubble contrast agent on breast tumors: Computer assisted quantitative assessment with color Doppler US-early experience, Radiology, 208, pp. 485-489, (1998)

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