Stability of bone marrow stromal cells to low temperatures depending on degree of differentiation

被引:0
作者
Raydan M. [1 ]
Shubin N.A. [1 ]
Nikolaenko N.S. [1 ]
Blinova M.I. [1 ]
Prokhorov G.G. [2 ]
Pinaev G.P. [1 ]
机构
[1] Institute of Cytology, Russian Academy of Sciences, St. Petersburg
[2] International Institute of Cryomedicine, St. Petersburg
关键词
adipogenic and osteogenic differentiation; BMSC; low temperature;
D O I
10.1134/S1990519X11030084
中图分类号
学科分类号
摘要
Based on a previous study of the stability of a heterogenous population of keratinocytes against cold depending on their degree of differentiation, we studied in vitro the stability of rat bone marrow stem cells (BMSCs) against cold before and after their differentiation in the adipogenic or osteogenic direction. It was shown that, after the induction of differentiation, BMSCs were least stable against the action of low temperatures than the undifferentiated cells. The obtained data can serve as a basis for the further study of processes and mechanisms that affect the stability of BMSCs against cold depending on their degree of differentiation. © 2011 Pleiades Publishing, Ltd.
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页码:294 / 299
页数:5
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