NK cell lymphoma, nasal type, with massive lung involvement: A case report

被引:10
作者
Morovic A. [1 ]
Aurer I. [2 ]
Dotlic S. [4 ]
Weisenburger D.D. [3 ]
Nola M. [4 ]
机构
[1] Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267
[2] Department of Internal Medicine, Zagreb University Hospital Center, Zagreb 10000
[3] Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198
[4] Department of Pathology, Zagreb University Hospital Center, Zagreb 10000
关键词
Epstein-Barr virus; Extranodal NK/T lymphoma; Lung involvement;
D O I
10.1007/s12308-009-0050-z
中图分类号
学科分类号
摘要
Extranodal NK/T cell lymphoma, nasal type, is an Epstein-Barr virus-associated lymphoma that most commonly involves the nasal cavity and upper respiratory tract. Lung involvement by NK/T cell lymphoma is rare and seldom reported in the literature. We describe the unusual case of a 41-year-old male with NK cell lymphoma, nasal type, who presented with massive secondary lung involvement 2.5 years after the detection of a retroperitoneal mass. The diagnosis was made by open lung biopsy. Despite aggressive treatment, the patient died shortly after the initiation of therapy. Lung involvement by NK/T cell lymphoma occurs most commonly as part of widely disseminated disease and carries a poor prognosis for the patient. Novel agents and innovative therapies need to be developed for this aggressive lymphoma. © 2009 Springer-Verlag.
引用
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页码:19 / 22
页数:3
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