Effect of physiological doses of oral vitamin B12 on plasma homocysteine: a randomized, placebo-controlled, double-blind trial in India

被引:0
作者
U S Deshmukh
C V Joglekar
H G Lubree
L V Ramdas
D S Bhat
S S Naik
P S Hardikar
D A Raut
T B Konde
A K Wills
A A Jackson
H Refsum
A S Nanivadekar
C H Fall
C S Yajnik
机构
[1] Diabetes Unit,Department of Physiology
[2] King Edward Memorial Hospital Research Centre,Department of Nutrition
[3] MRC Epidemiology Resource Centre,undefined
[4] University of Southampton,undefined
[5] Southampton General Hospital,undefined
[6] Institute of Human Nutrition,undefined
[7] University of Southampton,undefined
[8] Southampton General Hospital,undefined
[9] Anatomy and Genetics,undefined
[10] University of Oxford,undefined
[11] Institute of Basic Medical Sciences,undefined
[12] University of Oslo,undefined
来源
European Journal of Clinical Nutrition | 2010年 / 64卷
关键词
cyanocobalamin; folic acid; homocysteine; randomized controlled trial; South Asian Indians; vitamin B;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:495 / 502
页数:7
相关论文
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[1]  
Bhat DS(2009)Increases in plasma holotranscobalamin can be used to assess vitamin B-12 absorption in individuals with low plasma vitamin B-12 J Nutr 139 2119-2123
[2]  
Thuse NV(2008)Vitamin B12 status of pregnant Indian women and cognitive function in their 9-year-old children Food Nutr Bull 29 249-254
[3]  
Lubree HG(2007)Very low oral doses of vitamin B-12 increase serum concentrations in elderly subjects with food-bound vitamin B-12 malabsorption J Nutr 137 373-378
[4]  
Joglekar CV(2006)A daily intake of approximately 6 microg vitamin B-12 appears to saturate all the vitamin B-12-related variables in Danish postmenopausal women Am J Clin Nutr 83 52-58
[5]  
Naik SS(2008)Efficacy and safety of fortification and supplementation with vitamin B12: biochemical and physiological effects Food Nutr Bull 29 S177-S187
[6]  
Ramdas LV(2000)Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men Lancet 355 523-527
[7]  
Bhate V(2003)Hyperhomocysteinemia in Asian Indians living in the United States J Clin Endocrinol Metab 88 1089-1095
[8]  
Deshpande S(2004)Vitamin B12 and folate deficiency in later life Age Ageing 33 34-41
[9]  
Bhat D(2005)Effect of supplementation with cobalamin carried either by a milk product or a capsule in mildly cobalamin-deficient elderly Dutch persons Am J Clin Nutr 82 568-574
[10]  
Joshi N(2005)Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: a dose-finding trial Arch Intern Med 165 1167-1172