Effects of piracetam on pentylenetetrazol-kindling development, hippocampal potentiation phenomena and kindling-induced learning deficit

被引：0

作者：

H. Rüthrich

G. Grecksch

M. Krug

机构：

[1] Otto-von-Guericke University Magdeburg,

[2] Faculty of Medicine,undefined

[3] Institute of Pharmacology and Toxicology,undefined

[4] Leipziger Str. 44,undefined

[5] D-39120 Magdeburg,undefined

[6] Germany,undefined

来源：

Naunyn-Schmiedeberg's Archives of Pharmacology | 1999年 / 360卷

关键词：

Chemical kindling Pentylenetetrazol Piracetam Field potentials Hippocampus Potentiation Learning rat;

D O I：

暂无

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学科分类号：

摘要：

Kindling is a generally accepted model for studying epilepsy development in the context of overexpression of processes of neuronal plasticity. In previous studies we have shown that establishment of kindling by repeated application of subconvulsive doses of pentylenetetrazol (PTZ) also led to marked changes in hippocampal excitability and an impairment in learning behaviour.

引用

页码：413 / 420

页数：7