Isolation of new polyketide metabolites, linearolides A and B, from Streptomyces sp. RK95-74

被引：0

作者：

Masashi Ueki

Naofumi Koshiro

Harumi Aono

Makoto Kawatani

Masakazu Uramoto

Hisashi Kawasaki

Hiroyuki Osada

机构：

[1] Antibiotics Laboratory,Department of Green and Sustainable Chemistry

[2] Chemical Biology Core Facility,undefined

[3] RIKEN ASI,undefined

[4] Faculty of Engineering,undefined

[5] Tokyo Denki University,undefined

来源：

The Journal of Antibiotics | 2013年 / 66卷

关键词：

polyketide;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Although all Streptomyces strains are now thought to have 20–30 gene clusters for secondary metabolite biosynthesis, we cannot actually identify so many kinds of metabolites from one strain by conventional methods. Using Streptomyces sp. RK95-74, previously found as a cytotrienin producer, we searched new metabolites other than cytotrienin derivatives. Following the cultivation with new media and the peak-guided fractionation, we have found new compounds with new polyketide scaffold, named linearolides A and B.

引用

页码：333 / 337

页数：4

共 20 条

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