Early infections after autologous transplantation for haematological malignancies

被引:0
作者
I Schiødt
O J Bergmann
H E Johnsen
N E Hansen
机构
[1] Herlev Hospital/University of Copenhagen,Department of Haematology
来源
Medical Oncology | 1998年 / 15卷
关键词
early infections; autologous transplantation; bone marrow; peripheral blood stem cells; haematological malignancies;
D O I
暂无
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学科分类号
摘要
The purpose of this study was to evaluate the early infectious complications following autologous transplantation in haematoiogica! patients. Sixty-one patients who underwent either autologous bone marrow (BM; 28 patients) or peripheral blood stem cell (PBSC; 33 patients) transplantation for haematological malignancies were reviewed retrospectively. Engraftment happened significantly faster and the length of hospital stay was shorter in the PBSC group compared with the BM group. All patients in the study developed fever and all but two experienced temperatures ≥ 38.5°C. Overall, 57 patients had signs of oral mucositis, 23 with ulceration. Twenty patients had bacteraemia, 12 developed pneumonia, 6 systemic fungal infection. No major differences were found between the two groups in distribution or incidence of infections. This study indicates that the use of peripheral blood stem cells results in faster engraftment and shorter hospital stay, whereas the effect on the incidence of early infections seems to be unaffected.
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页码:103 / 108
页数:5
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