Myopericarditis complicated by pulmonary embolism in an immunocompetent patient with acute cytomegalovirus infection: A case report

被引：3
作者：
Vandamme Y.M. [1 ,4 ]
Ducancelle A. [2 ]
Biere L. [3 ]
Viot N. [3 ]
Rouleau F. [3 ]
Delbos V. [1 ]
Abgueguen P. [1 ]
机构：
[1] Department of Infectious Diseases and Internal Medicine, Centre Hospitalier Universitaire d'Angers, 49933 Angers, Cedex 9
[2] Department of Bacteriology and Virology, Centre Hospitalier Universitaire d'Angers, 49933 Angers, Cedex 9
[3] Department of Cardiology, Centre Hospitalier Universitaire d'Angers, 49933 Angers, Cedex 9
[4] Department of Infectious and Tropical Diseases, CHU Angers, 49933 Angers, Cedex 9
来源：
BMC Research Notes | / 7卷 / 1期
关键词：
Cytomegalovirus; Immunocompetent patient; Myopericarditis; Pulmonary embolism; Thrombosis;
D O I：
10.1186/1756-0500-7-193
中图分类号：
学科分类号：
摘要：
Background: Primary acute cytomegalovirus infection in immunocompetent patients is common worldwide. Infection is most often asymptomatic or occurs sub-clinically with a self-limited mononucleosis-like syndrome. More rarely, the infection may lead to severe organ complications with pneumonia, myocarditis, pericarditis, colitis and hemolytic anemia. Recent cases of cytomegalovirus- associated thrombosis have also been reported sporadically in the medical literature. Case presentation. We report here a case of simultaneous myopericarditis and pulmonary embolism in a 30-year-old man with no medical history. The patient was not immunocompromised. We discuss the possible role of acute cytomegalovirus infection in the induction of vascular damage and review relevant cases in the literature. Conclusion: Thrombosis in patients with acute cytomegalovirus infection may be more frequent than is generally thought. Physicians need to be aware of the possible association between acute cytomegalovirus and thrombosis in immunocompetent patients, especially in the presence of severe systemic infection, as our case illustrates. © 2014 Vandamme et al.; licensee BioMed Central Ltd.
引用
收藏
相关论文
共 48 条
  • [11] Schmitz H., Enders G., Cytomegalovirus as a frequent cause of Guillain-Barre syndrome, J Med Virol, 1, 1, pp. 21-27, (1977)
  • [12] Eddleston M., Peacock S., Juniper M., Warrell D.A., Severe cytomegalovirus infection in immunocompetent patients, Clinical Infectious Diseases, 24, 1, pp. 52-56, (1997)
  • [13] Abgueguen P., Delbos V., Chennebault J.M., Payan C., Pichard E., Vascular thrombosis and acute cytomegalovirus infection in immunocompetent patients: Report of 2 cases and literature review, Clin Infect Dis, 36, 11, (2003)
  • [14] Justo D., Finn T., Atzmony L., Guy N., Steinvil A., Thrombosis associated with acute cytomegalovirus infection: A meta-analysis, Eur J Intern Med, 22, 2, pp. 195-199, (2011)
  • [15] Abgueguen P., Delbos V., Ducancelle A., Jomaa S., Fanello S., Pichard E., Venous thrombosis in immunocompetent patients with acute cytomegalovirus infection: A complication that may be underestimated, Clin Microbiol Infect, 16, 7, pp. 851-854, (2010)
  • [16] Rasanen V., Saikku P., [Cytomegalovirus hepatitis and pericarditis], Duodecim, 84, 4, pp. 270-273, (1968)
  • [17] Sterner G., Agell B.O., Wahren B., Espmark A., Acquired cytomegalovirus infection in older children and adults. A clinical study of hospitalized patients, Scand J Infect Dis, 2, 2, pp. 95-103, (1970)
  • [18] Wilson R.S., Morris T.H., Rees J.R., Cytomegalovirus myocarditis, Br Heart J, 34, 8, pp. 865-868, (1972)
  • [19] Vanstechelman F., Vandekerckhove H., Cytomegalovirus myocarditis in an immunocompetent patient, Acta Cardiol, 67, 2, pp. 257-260, (2012)
  • [20] Baumgratz J.F., Vila J.H., Silva J.P., Fonseca L., Rodrigues E.A., Knobel E., Cardiogenic shock due to cytomegalovirus myocarditis: Successful clinical treatment, Rev Bras Cir Cardiovasc, 25, 2, pp. 149-153, (2010)
12345