Blood-to-Retina Transport of Fluorescence-Labeled Verapamil at the Blood-Retinal Barrier

被引:0
作者
Yoshiyuki Kubo
Ayumi Nakazawa
Shin-ichi Akanuma
Ken-ichi Hosoya
机构
[1] University of Toyama,Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences
来源
Pharmaceutical Research | 2018年 / 35卷
关键词
blood-retinal barrier; lysosomal trapping; neuroprotectants; organic cation transport; verapamil;
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[1]  
Chao HM(2000)An investigation into the potential mechanisms underlying the neuroprotective effect of clonidine in the retina Brain Res 877 47-57
[2]  
Chidlow G(2011)Role of the adrenergic system in a mouse model of oxygen-induced retinopathy: antiangiogenic effects of beta-adrenoreceptor blockade Invest Ophthalmol Vis Sci 52 155-170
[3]  
Melena J(2011)Strategies for therapy of retinal diseases using systemic drug delivery: relevance of transporters at the blood-retinal barrier Expert Opin Drug Deliv 8 1571-1587
[4]  
Wood JP(2004)The blood-retinal barriers system. Basic concepts and clinical evaluation Exp Eye Res 78 715-721
[5]  
Osborne NN(1994)Blood-eye barriers in the rat: correlation of ultrastructure with function J Comp Neurol 340 566-576
[6]  
Ristori C(2001)Conditionally immortalized retinal capillary endothelial cell lines (TR-iBRB) expressing differentiated endothelial cell functions derived from a transgenic rat Exp Eye Res 72 163-172
[7]  
Filippi L(2005)Advances in the cell biology of transport via the inner blood-retinal barrier: establishment of cell lines and transport functions Biol Pharm Bull 28 1-8
[8]  
Dal Monte M(2015)Impact of cationic amino acid transporter 1 on blood-retinal barrier transport of L-ornithine Invest Ophthalmol Vis Sci 56 5925-5932
[9]  
Martini D(2017)Blood-to-retina transport of riboflavin via RFVTs at the inner blood-retinal barrier Drug Metab Pharmacokinet 32 92-99
[10]  
Cammalleri M(2017)Influx transport of cationic drug at the blood-retinal barrier: impact on the retinal delivery of neuroprotectants Biol Pharm Bull 40 1139-1145