Octreotide reduces hepatic, renal and breast cystic volume in autosomal-dominant polycystic kidney disease

被引:0
作者
Ramón Peces
Emilio Cuesta-López
Carlos Peces
Virginia Pérez-Dueñas
Cristina Vega-Cabrera
Rafael Selgas
机构
[1] Hospital Universitario La Paz,Servicio de Nefrología
[2] Hospital Universitario La Paz,Servicio de Radiología
[3] Area de Tecnología de la Información,undefined
[4] SESCAM,undefined
来源
International Urology and Nephrology | 2011年 / 43卷
关键词
ADPKD; cAMP; Fibrocystic disease of breast; Octreotide; Renal function; Volume change;
D O I
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学科分类号
摘要
A 43-year-old woman with autosomal-dominant polycystic kidney disease (ADPKD) received octreotide for 12 months, and this was associated with a 6.3% reduction in liver volume, an 8% reduction in total kidney volume and stabilization of renal function. There was also a reduction of cyst size in fibrocystic disease of breast. These data suggest that the cyst fluid accumulation in different organs from patients with ADPKD is a dynamic process which can be reversed by octreotide. This is the first report of a case of simultaneous reduction in hepatic, renal and breast cystic volume with preservation of renal function in a patient with ADPKD receiving octreotide.
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页码:565 / 569
页数:4
相关论文
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