Preparation and Characterization of Carboxyl Functionalized Fluorescent Mesoporous Silica Nanoparticles Containing 8-Hydroxyquinolinate Zinc Complexes

被引：0
作者：
Wanxia Wang
Youyun Wang
Yu Wang
Hongda Zhu
Honghao Sun
Mingxing Liu
机构：
[1] Hubei University of Technology,Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei Provincial Cooperative Innovation Center of Industrial Fermentation, National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Hubei K
来源：
Journal of Wuhan University of Technology-Mater. Sci. Ed. | 2019年 / 34卷
关键词：
mesoporous silica nanoparticles; 8-hydroxyquinolinate zinc complexes; fluorescent; carboxyl functionalization; synthesis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Fluorescent mesoporous silica nanoparticles functionalized with carboxyl group (Znq-CMS-COOH) were successfully synthesized by in situ formation route of 8-hydroxyquinolinate zinc complexes in channels of mesoporous silica nanoparticles and post-grafting of carboxyl group on the surface. Moreover, the particle size and structural properties of Znq-CMS-COOH were characterized by transmission electron microscopy (TEM), field emission scanning electron microscopy (FE-SEM), dynamic light scattering (DLS). Fourier transform infrared spectroscopy (FT-IR), UV-vis spectrometer, fluorescence spectrometer and nitrogen adsorption-desorption measurements. The obtained results suggest that the Znq-CMS-COOH presents the uniform spherical shape with the mean diameter of about 85 nm and the obvious wormhole arrangement mesoporous. In addition, the Znq-CMS-COOH possesses green fluorescence with the emission peaks at 495 nm. So the Znq-CMS-COOH, which is beneficial to further modification and tracing, might be a great potential carrier for applying in drug delivery system in the future.
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页码：973 / 978
页数：5
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