Evolution in Biosensors for Cancers Biomarkers Detection: A Review

被引：0
作者：
Alharthi S.D. [1 ]
Bijukumar D. [1 ]
Prasad S. [2 ]
Khan A.M. [3 ]
Mathew M.T. [1 ]
机构：
[1] Department of Biomedical Science, University of Illinois at Chicago at Rockford, 1601 Parkview Avenue, Rockford, 61107, IL
[2] Department of Bioengineering, University of Texas in Dallas, UTD, Dallas
[3] Center for Cancer Care, OSF, Rockford
来源：
Journal of Bio- and Tribo-Corrosion | 2021年 / 7卷 / 02期
基金：
美国国家卫生研究院;
关键词：
Biomarker; Biosensor; Cancer; Electrochemical; Optical; Piezoelectric;
D O I：
10.1007/s40735-020-00463-7
中图分类号：
学科分类号：
摘要：
Advancement in the field of biosensor/bioelectronics technology has been exploited in the biomedical field for diagnostics and therapy. The potential of this technology in identifying molecular targets has become projected as new generation diagnostics particularly in cancer diagnostics. Cancer being the second cause of death among all diseases in the US and worldwide, the early diagnosis becomes the growing research area in this field. The conventional techniques to detect cancer are expensive, painful, time-consuming, and low sensitivity and specificity. Recently, investigators have developed several types of biosensors to detect specific molecular markers of cancer. Biosensors are classified as point of care/diagnostic tools that can be conducted at home by the patient. This review describes a detailed investigation of different cancer biomarkers and various biosensors developed to detect the biomarkers, the principles, and detection limits, which could assist to detect cancer in early stages. © 2021, The Author(s), under exclusive licence to Springer Nature Switzerland AG part of Springer Nature.
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