Hematopoietic stem and progenitor cells: their mobilization and homing to bone marrow and peripheral tissue

被引：0
作者：
Christian Schulz
Ulrich H. von Andrian
Steffen Massberg
机构：
[1] Technische Universität München,Deutsches Herzzentrum
[2] Harvard Medical School,Immune Disease Institute and Department of Pathology
来源：
Immunologic Research | 2009年 / 44卷
关键词：
Hematopoietic stem cells; Progenitor cells; Migration; Homing; Bone marrow; Peripheral tissue;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Hematopoietic stem and progenitor cells (HSPCs) are a rare population of precursor cells that possess the capacity for self-renewal and multilineage differentiation. In the bone marrow (BM), HSPCs warrant blood cell homeostasis. In addition, they may also replenish tissue-resident myeloid cells and directly participate in innate immune responses once they home to peripheral tissues. In this review, we summarize recent data on the signaling molecules that modulate the mobilization of HSPCs from BM and their migration to peripheral tissues.
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页码：160 / 168
页数：8
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