Intracellular IL-1Ra exhibits unique antiinflammatory properties

被引：0
作者：
WP Arend
N Banda
M Muggli
D Sheppard
C Guthridge
K Santopietro
D Bech-Otschir
W Dubiel
机构：
[1] University of Colorado Health Sciences Center,Division of Rheumatology, Department of Medicine
[2] Humboldt University,Division of Molecular Biology, Department of Surgery
来源：
Arthritis Res Ther | / 6卷 / Suppl 3期
关键词：
Intestinal Epithelial Cell Line; COP9 Signalosome; Human Synovial Fibroblast; Glycerol Gradient; Matrix Metalloproteinase Production;
D O I：
10.1186/ar1386
中图分类号：
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  • [1] Bech-Otschir D(2002)The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis J Cell Sci 115 467-473
  • [2] Seeger M(2003)Intracellular IL-1Ra type I inhibits IL-1-induced IL-6 and IL-8 production in Caco-2 intestinal epithelial cells through inhibition of p38 mitogen-activated protein kinase and NF-κB pathways Cytokine 23 31-40
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