AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3)

被引：0

作者：

A. Nerstedt

A. Johansson

C. X. Andersson

E. Cansby

U. Smith

M. Mahlapuu

机构：

[1] University of Gothenburg,The Lundberg Laboratory for Diabetes Research, Center of Excellence for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine/Diabetes, The Sahlgrenska Academy

来源：

Diabetologia | 2010年 / 53卷

关键词：

AMP-activated protein kinase; Inflammation; Interleukin-6; Liver; Type 2 diabetes;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：2406 / 2416

页数：10

共 19 条

[1] AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3)
Nerstedt, A.
Johansson, A.
Andersson, C. X.
Cansby, E.
Smith, U.
Mahlapuu, M.
DIABETOLOGIA, 2010, 53 (11) : 2406 - 2416
[2] Human IL6 stimulates bovine satellite cell proliferation through a Signal transducer and activator of transcription 3 (STAT3)-dependent mechanism
Brandt, A. M.
Kania, J. M.
Reinholt, B. M.
Johnson, S. E.
DOMESTIC ANIMAL ENDOCRINOLOGY, 2018, 62 : 32 - 38
[3] Flavanoids induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene and suppress IL-6-activated signal transducer and activator of transcription 3 (STAT3) activation in vascular endothelial cells
Wiejak, Jolanta
Dunlop, Julia
Mackay, Simon P.
Yarwood, Stephen J.
BIOCHEMICAL JOURNAL, 2013, 454 : 283 - 293
[4] Takinib Inhibits Inflammation in Human Rheumatoid Arthritis Synovial Fibroblasts by Targeting the Janus Kinase-Signal Transducer and Activator of Transcription 3 (JAK/STAT3) Pathway
Panipinto, Paul M.
Singh, Anil K.
Shaikh, Farheen S.
Siegel, Ruby J.
Chourasia, Mukesh
Ahmed, Salahuddin
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (22)
[5] Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation
Aparicio-Siegmund, Samadhi
Sommer, Jan
Monhasery, Niloufar
Schwanbeck, Ralf
Keil, Eric
Finkenstaedt, David
Pfeffer, Klaus
Rose-John, Stefan
Scheller, Juergen
Garbers, Christoph
ONCOTARGET, 2014, 5 (08) : 2131 - 2148
[6] Identification and mechanistic exploration of key anti-inflammatory molecules in American ginseng: Impacts on signal transducer and activator of transcription 3 STAT3 phosphorylation and macrophage polarization
Li, Taiping
Zhang, Yougang
Dong, Rong
Bi, Wenjie
Wang, Songsong
Zeng, Kewu
Han, Liwen
PHYTOTHERAPY RESEARCH, 2024, 38 (08) : 4307 - 4320
[7] IL-6, a risk factor for hepatocellular carcinoma FLLL32 inhibits IL-6-induced STAT3 phosphorylation in human hepatocellular cancer cells
Liu, Yan
Fuchs, James
Li, Chenglong
Lin, Jiayuh
CELL CYCLE, 2010, 9 (17) : 3423 - 3427
[8] Atorvastatin Prevents Myocardial Fibrosis in Spontaneous Hypertension via Interleukin-6 (IL-6)/Signal Transducer and Activator of Transcription 3 (STAT3)/Endothelin-1 (ET-1) Pathway
Fang, Tianfu
Guo, Baoliang
Xue, Lujing
Wang, Li
MEDICAL SCIENCE MONITOR, 2019, 25 : 318 - 323
[9] A Signal Transducer and Activator of Transcription 3•Nuclear Factor κB (Stat3•NFκB) Complex Is Necessary for the Expression of Fascin in Metastatic Breast Cancer Cells in Response to Interleukin (IL)-6 and Tumor Necrosis Factor (TNF)-α
Snyder, Marylynn
Huang, Jianyun
Huang, Xin-Yun
Zhang, J. Jillian
JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (43) : 30082 - 30089
[10] Brazilian propolis inhibits the differentiation of Th17 cells by inhibition of interleukin-6-induced phosphorylation of signal transducer and activator of transcription 3
Okamoto, Yoshihiro
Tanaka, Mayuri
Fukui, Takashi
Masuzawa, Toshiyuki
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, 2012, 34 (05) : 803 - 809

← 1 2 →