Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma

被引：0
作者：
Jose Pulido
Timothy Kottke
Jill Thompson
Feorillo Galivo
Phonphimon Wongthida
Rosa Maria Diaz
Diana Rommelfanger
Elizabeth Ilett
Larry Pease
Hardev Pandha
Kevin Harrington
Peter Selby
Alan Melcher
Richard Vile
机构：
[1] Mayo Clinic,Department of Molecular Medicine
[2] Mayo Clinic,Department of Ophthalmology and Ocular Oncology
[3] Virology and Cell Technology,Department of Immunology
[4] National Center for Genetic Engineering and Biotechnology,undefined
[5] Cancer Research UK Clinical Centre,undefined
[6] St. James' University Hospital,undefined
[7] Mayo Clinic,undefined
[8] University of Surrey,undefined
[9] The Institute of Cancer Research,undefined
来源：
Nature Biotechnology | 2012年 / 30卷
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摘要：
Vaccination with a virus-expressed cDNA library derived from normal prostate cells can cure established prostate cancer in mouse models. Pulido et al. extend this approach and identify specific tumor-associated antigens from tumor-derived virus-expressed cDNA libraries that can be used in combination to cure established melanoma in mice.
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页码：337 / 343
页数：6
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