Isolation and Identification of a New Thymic Peptide from Calf Thymus

被引:0
作者
Xi-Ming Qin
Ming-Xing Duan
Bin Deng
Xi-Cheng Liu
Qiang-Zhe Zhang
Zheng Liu
Hong-Xuan He
机构
[1] Department of Biological Sciences and Biotechnology,State Key Laboratory of Biomembranes and Membrane Biotechnology
[2] Tsinghua University,undefined
来源
Biochemistry (Moscow) | 2004年 / 69卷
关键词
thymus; TAF-II; E-rosette assay; thymic peptide;
D O I
暂无
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学科分类号
摘要
Various thymic peptides (including thymulin, thymic humoral factor, thymopoietin, etc.) play important roles in the process of T cell maturation and development. We isolated a new peptide from calf thymus and named it thymus activity factor II (TAF-II). A yield of 0.92 mg of TAF-II was purified from 500 g calf thymus. Analysis by LC/MSD-Trap showed the amino acid sequence of this hexapeptide to be Glu-Ala-Lys-Ser-Gln-Gly-OH with molecular weight 618.5 daltons. We have also begun to investigate the influence of TAF-II.
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页码:921 / 925
页数:4
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