Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress

被引:0
作者
Aadil Bharwani
M. Firoz Mian
Michael G. Surette
John Bienenstock
Paul Forsythe
机构
[1] McMaster University,Department of Pathology & Molecular Medicine
[2] McMaster Brain-Body Institute,Department of Medicine
[3] The Research Institute of St. Joseph’s Hamilton,undefined
[4] Michael G. DeGroote School of Medicine,undefined
[5] McMaster University,undefined
[6] McMaster University,undefined
[7] The Brain-Body Institute,undefined
[8] Farncombe Family Digestive Health Research Institute,undefined
[9] McMaster University,undefined
[10] Firestone Institute for Respiratory Health,undefined
[11] St. Joseph’s Healthcare Hamilton,undefined
来源
BMC Medicine | / 15卷
关键词
Chronic social defeat; Microbiota; Behaviour; Immune system; Gut-brain axis; Psychiatric disease;
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  • [1] McEwen BS(1998)Protective and damaging effects of stress mediators N Engl J Med Mass Med Soc. 338 171-9
  • [2] Duffy LC(1991)Relevance of major stress events as an indicator of disease activity prevalence in inflammatory bowel disease Behav Med. 17 101-10
  • [3] Zielezny MA(1997)Trauma and the gut: interactions between stressful experience and intestinal function Gut. 40 704-6
  • [4] Marshall JR(2009)Exposure to severe wartime conditions in early life is associated with an increased risk of irritable bowel syndrome: a population-based cohort study Am. J. Gastroenterol. 104 2250-48
  • [5] Byers TE(2006)Ecological and evolutionary forces shaping microbial diversity in the human intestine Cell. 124 837-69
  • [6] Weiser MM(2013)Voices from within: gut microbes and the CNS Cell Mol Life Sci. 70 55-42
  • [7] Phillips JF(2012)The interplay between the intestinal microbiota and the brain Nat Rev Microbiol. 10 735-12
  • [8] Stam R(2012)Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour Nat Rev Neurosci. 13 701-609
  • [9] Akkermans LM(2011)The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice Gastroenterology. 141 599-5
  • [10] Wiegant VM(2011)Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve Proc Natl Acad Sci. 108 16050-9