Application of droplet digital PCR for the detection of vector copy number in clinical CAR/TCR T cell products

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作者
Alex Lu
Hui Liu
Rongye Shi
Yihua Cai
Jinxia Ma
Lipei Shao
Victor Rong
Nikolaos Gkitsas
Hong Lei
Steven L. Highfill
Sandhya Panch
David F. Stroncek
Ping Jin
机构
[1] NIH Clinical Center,Center for Cellular Engineering, Department of Transfusion Medicine and Cellular Engineering
关键词
Droplet digital PCR; Vector copy number; Genetically engineered T cells; Gene therapy; Chimeric antigen receptor (CAR) T cells; T Cell Receptor (TCR)-engineered T cells; Cellular cancer immunotherapy;
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