Vitamin E δ-tocotrienol sensitizes human pancreatic cancer cells to TRAIL-induced apoptosis through proteasome-mediated down-regulation of c-FLIPs

被引:0
作者
Rony A. Francois
Anying Zhang
Kazim Husain
Chen Wang
Sean Hutchinson
Michael Kongnyuy
Surinder K. Batra
Domenico Coppola
Said M. Sebti
Mokenge P. Malafa
机构
[1] H. Lee Moffitt Cancer Center and Research Institute,Gastrointestinal Oncology Program, Department of Gastrointestinal Oncology
[2] University of Electronic Science and Technology of China,Department of Life Science and Technology
[3] Tianjin Medical University Cancer Institute and Hospital,Department of Breast Oncology
[4] University of Nebraska Medical Center,Department of Biochemistry and Molecular Biology, College of Medicine
[5] H. Lee Moffitt Cancer Center and Research Institute,Department of Anatomical Pathology
[6] H. Lee Moffitt Cancer Center and Research Institute,Drug Discovery Program
来源
Cancer Cell International | / 19卷
关键词
δ-Tocotrienol; Pancreatic cancer; Apoptosis; TRAIL; c-FLIP;
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