Epithelioid Hemangioendothelioma of the Maxillary Sinus

被引：3

作者：

Avadhani V. ^{[1
]}

Loftus P.A. ^{[2
]}

Meltzer D. ^{[3
]}

Wang B. ^{[1
]}

Tabaee A. ^{[4
]}

机构：

[1] Department of Pathology and Laboratory Medicine, Mount Sinai Beth Israel, New York, NY

[2] Department of Otorhinolaryngology – Head and Neck Surgery, Albert Einstein College of Medicine, New York, NY

[3] Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY

[4] Department of Otolaryngology, Icahn School of Medicine at Mount Sinai, 10 Union Square East, New York, 10003, NY

来源：

Head and Neck Pathology | 2016年 / 10卷 / 2期

关键词：

Epistaxis; Epithelioid hemangioendothelioma; Maxillary sinus; Neoplasm; Paranasal sinus;

D O I：

10.1007/s12105-015-0633-1

中图分类号：

学科分类号：

摘要：

The clinical course and pathologic features of a 72 year old female who presented with epistaxis are presented. Radiographic findings were notable for a large, soft tissue lesion filling the maxillary sinus with significant bony erosion and expansion. The patient was ultimately diagnosed with epithelioid hemangioendothelioma (EHE) and underwent endoscopic resection. She has no evidence of local, regional or distant recurrence 14 months post-surgery. The rarity of this neoplasm, the unusual anatomic location and non-specific symptoms present diagnostic and management challenges. Epithelioid vascular tumors encompass a spectrum of benign and malignant tumors. EHE itself is thought to have an intermediate malignant behavior pattern, though cases with indolent behavior have been reported. Differentiation of EHE from other lesions has historically based on histopathology. Additionally, recent studies have described a recurrent genetic fusion WWTR1–CAMTA1 in EHE, involving t(1;3) (p36;q25). This represents the second reported case of EHE arising in a paranasal sinus. The histopathologic findings of this lesion are reviewed. © 2015, Springer Science+Business Media New York.

引用

页码：229 / 232

页数：3

共 16 条

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