Plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene

被引:0
作者
Ana Afonso
Zoraima Neto
Helena Castro
Dinora Lopes
Ana C Alves
Ana M Tomás
Virgílio D Rosário
机构
[1] Centro de Malária e Doenças Tropicais - Associated Laboratory (CMDT-LA)/IHMT/UEI Malaria,IBMC
[2] Universidade do Porto, Instituto de Biologia Molecular e Celular
[3] Unit of Medical Parasitology and Microbiology (UPMM)/IHMT,ICBAS
[4] Previously a member of Centro de Malária e Doenças Tropicais - Associated Laboratory (CMDT-LA)/IHMT/UEI Malaria, Instituto de Ciências Biomédicas Abel Salazar
[5] Universidade do Porto,undefined
来源
Malaria Journal | / 9卷
关键词
Chloroquine; Artesunate; Resistant Parasite; Pyrimethamine; Atovaquone;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 248 条
[11]  
Vaidya AB(2003)Structural features of Malar J 2 5-1078
[12]  
Vaidya AB(1995) cytochrome b that may underlie susceptibility to 8-aminoquinolines and hydroxynaphthoquinones J Antimicrob Chemother 36 1073-66
[13]  
Mather MW(1996)A mechanism for the synergistic antimalarial action of atovaquone and proguanil Am J Trop Med Hyg 54 62-89
[14]  
Kessl JJ(2002)Different mutation patterns of atovaquone resistance to Malar J 1 1-363
[15]  
Ha KH(2003) in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker Mol Cell Probes 17 85-1546
[16]  
Merritt AK(2004)Evaluation of atovaquone in the treatment of patients with uncomplicated Trop Med Int Health 9 361-2281
[17]  
Lange BB(2006) malaria Malar J 5 30-2604
[18]  
Hill P(2004)Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand J Infect Dis 190 1541-898
[19]  
Meunier B(2007)Malarone treatment failure and in vitro confirmation of resistance of Antimicrob Agents Chemother 51 2280-629
[20]  
Meshnick SR(2006) isolate from Lagos, Nigeria Microbes Infect 8 2599-409