Synthesis and antimicrobial activities of novel ferrocenyl dispiropyrrolidines and pyrrolizidines

被引：0
|
作者：
Subban Kathiravan
Raghavachary Raghunathan
Gopalakrishnan Suresh
Ganesan Vijaiyan Siva
机构：
[1] University of Madras,Department of Organic Chemistry
[2] Guindy Campus,Department of Bio
[3] University of Madras,technology
[4] Guindy Campus,undefined
来源：
Medicinal Chemistry Research | 2012年 / 21卷
关键词：
Ferrocene; 1,3-Dipolar cycloaddition; Baylis–Hillman adduct; Antimicrobial activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A series of novel ferrocenyl spiropyrolidines and pyrrolizidines have been synthesized through 1,3-dipolar cycloaddition reaction of azomethine ylide generated from amino acids and various 1,2-diketones with ferrocenyl Baylis–Hillman adducts as dipolarophiles. The synthesized cycloadducts were evaluated for antimicrobial activities. Compounds 12, 13, 14, and 18 showed relatively good antimicrobial activity.
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页码：3170 / 3176
页数：6
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